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ONCOGENE PROTEIN P21(RAS)
Descriptors Found:
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DeCS
Descriptor
English
:
Oncogene Protein p21(ras)
Descriptor
Spanish
:
Proteína Oncogénica p21(ras)
Descriptor
Portuguese
:
Proteína Oncogênica p21(ras)
Synonyms
English
:
ras Oncogene Protein p21
p21(v-Ha-ras)
p21(v-Ki-ras)
Tree Number:
D08.811.277.040.330.300.400.500.300
D12.644.360.525.500.300
D12.776.157.325.515.500.300
D12.776.476.525.500.300
D12.776.624.664.520.750.710
D12.776.964.700.750.710
D12.776.964.775.750.710
Definition
English
:
Transforming protein encoded by ras
oncogenes
. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian
cells
.
Oncogene protein p21(ras)
has been directly implicated in human
neoplasms
, perhaps
accounting
for as much as 15-20% of all human tumors. This enzyme was formerly listed as EC 3.6.1.47.
Indexing Annotation
English
:
coord with specific virus
History Note
English
:
1990
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
24815
Unique Identifier:
D015689
Occurrence in VHL
:
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